The mission of the Li lab is to advance molecular understanding of human aging and age-related diseases such as Alzheimer's disease through discovery of candidate biomarkers and translation as clinical tests to improve clinical diagnosis, prognosis and treatment. In particularly, we will focus on development of innovative analytical tools and robust workflows that can be applied to reproducibly analyze large number of human biological samples, a critical first step toward successful biomarker discovery and translation. A main focus of the lab is to train next generation of translational scientists. We will create an environment that is conducive to scientific excellence, critical thinking, discipline, and teamwork.